Estimated HPV-Associated Burden Of Cancer
Cervical cancer accounts for over 86% of HPV-related cancers on a global basis.
There have been well documented differences of 10-fold variations in rates between countries within regions. These differences are due predominately to a combination of HPV prevalence and the presence of effectiveness of screening programs. For example, in a relative affluent area such as Northern Europe which has high rates of cancer registration, there is a 5-fold variation in the incidence between the high rates in Lithuania and the low rates in Finland.
700,000 occurred in HPV-associated cancers in the cervix, anus, penis, vulva, vagina, and oropharynx occur. An estimated 610,000 of these were attributed to HPV.
Of the 490,000 cases attributed to HPV in 2008, over 80% occurred in less developed regions.
Declines in cervical cancer are the results of effective screening procedures, and various social cultural factors including improving to access to care, increased age at marriage, family planning behavior, and improvements in education.
Cervical cancer is estimated to be the third most common female malignancy worldwide in 2008, with 530,000 new cases. Cervical cancer is less frequently then breast and large bowel cancers and is the fourth most common cause of female deaths from cancer, after breast, lung and large bowel cancers.
4.8% of all of the cancers which occur worldwide are attributable to HPV infection. There are 12.7 million new cancers which occurred in 2008.